Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitors.
Ras CAAX (C = cysteine, A = aliphatic amino acid, and X = any amino acid) peptidomimetic inhibitors of farnesyl protein transferase suppress Ras-dependent cell transformation by preventing farnesylation of the Ras oncoprotein. These compounds are potential anticancer agents for tumors associated wit...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
1995
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.10919 |
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