Activated Drosophila Ras1 is selectively suppressed by isoprenyl transferase inhibitors.

Ras CAAX (C = cysteine, A = aliphatic amino acid, and X = any amino acid) peptidomimetic inhibitors of farnesyl protein transferase suppress Ras-dependent cell transformation by preventing farnesylation of the Ras oncoprotein. These compounds are potential anticancer agents for tumors associated wit...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Kauffmann, R C, Qian, Y, Vogt, A, Sebti, S M, Hamilton, A D, Carthew, R W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40542/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479910/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.24.10919
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