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Mutations in the Main Cytoplasmic Loop of the GABA(A) Receptor α(4) and δ Subunits Have Opposite Effects on Surface Expression
We examined the role of putative trafficking sequences in two GABA(A) receptor subunits: α(4) and δ. These subunits assemble with a β subunit to form a subtype of GABA(A) receptor involved in generating the “tonic” outward current. Both α(4) and δ subunits contain dibasic retention motifs in homolog...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054001/ https://ncbi.nlm.nih.gov/pubmed/24723490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.092791 |
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