On the design of clone-based haplotyping

BACKGROUND: Haplotypes are important for assessing genealogy and disease susceptibility of individual genomes, but are difficult to obtain with routine sequencing approaches. Experimental haplotype reconstruction based on assembling fragments of individual chromosomes is promising, but with variable...

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Main Authors: Lo, Christine, Liu, Rui, Lee, Jehyuk, Robasky, Kimberly, Byrne, Susan, Lucchesi, Carolina, Aach, John, Church, George, Bafna, Vineet, Zhang, Kun
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2013
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053695/
https://ncbi.nlm.nih.gov/pubmed/24028704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2013-14-9-r100
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