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Quantitative reconstruction of leukocyte subsets using DNA methylation

BACKGROUND: Cell lineage-specific DNA methylation patterns distinguish normal human leukocyte subsets and can be used to detect and quantify these subsets in peripheral blood. We have developed an approach that uses DNA methylation to simultaneously quantify multiple leukocyte subsets, enabling inve...

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Autores principales: Accomando, William P, Wiencke, John K, Houseman, E Andres, Nelson, Heather H, Kelsey, Karl T
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4053693/
https://ncbi.nlm.nih.gov/pubmed/24598480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-3-r50
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