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Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective

BACKGROUND: The impact of cell-composition effects in analysis of DNA methylation data is now widely appreciated. With the availability of a reference data set consisting of DNA methylation measurements on isolated cell types, it is possible to impute cell proportions and adjust for them, but there...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Houseman, E Andres, Kelsey, Karl T, Wiencke, John K, Marsit, Carmen J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4392865/
https://ncbi.nlm.nih.gov/pubmed/25887114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0527-y
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