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DNA methylation arrays as surrogate measures of cell mixture distribution

BACKGROUND: There has been a long-standing need in biomedical research for a method that quantifies the normally mixed composition of leukocytes beyond what is possible by simple histological or flow cytometric assessments. The latter is restricted by the labile nature of protein epitopes, requireme...

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Detalhes bibliográficos
Main Authors: Houseman, Eugene Andres, Accomando, William P, Koestler, Devin C, Christensen, Brock C, Marsit, Carmen J, Nelson, Heather H, Wiencke, John K, Kelsey, Karl T
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532182/
https://ncbi.nlm.nih.gov/pubmed/22568884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-86
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