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A novel approach to the discovery of survival biomarkers in glioblastoma using a joint analysis of DNA methylation and gene expression

Glioblastoma multiforme (GBM) is the most aggressive of all brain tumors, with a median survival of less than 1.5 years. Recently, epigenetic alterations were found to play key roles in both glioma genesis and clinical outcome, demonstrating the need to integrate genetic and epigenetic data in predi...

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Detalhes bibliográficos
Main Authors: Smith, Ashley A, Huang, Yen-Tsung, Eliot, Melissa, Houseman, E Andres, Marsit, Carmen J, Wiencke, John K, Kelsey, Karl T
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4065185/
https://ncbi.nlm.nih.gov/pubmed/24670968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28571
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