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Development of a Novel Multiplex PCR Assay to Detect Functional Subtypes of KIR3DL1 Alleles
Among NK cell receptor-ligand partnerships, KIR3DL1 and HLA-Bw4 demonstrate the greatest diversity; permutations of their allelic combinations titrate NK reactivity. Balancing selection has maintained distinct subtypes of KIR3DL1 alleles in global populations, implying that each may provide unique f...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Public Library of Science
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4053526/ https://ncbi.nlm.nih.gov/pubmed/24919192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099543 |
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