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Distinct stages of the translation elongation cycle revealed by sequencing ribosome-protected mRNA fragments

During translation elongation, the ribosome ratchets along its mRNA template, incorporating each new amino acid and translocating from one codon to the next. The elongation cycle requires dramatic structural rearrangements of the ribosome. We show here that deep sequencing of ribosome-protected mRNA...

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Detalhes bibliográficos
Main Authors: Lareau, Liana F, Hite, Dustin H, Hogan, Gregory J, Brown, Patrick O
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052883/
https://ncbi.nlm.nih.gov/pubmed/24842990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01257
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