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Effects of Tet-induced Oxidation Products of 5-Methylcytosine on Dnmt1- and DNMT3a-mediated Cytosine Methylation
We investigated systematically the effects of Tet-induced oxidation products of 5-methylcytosine (5mC) on Dnmt1- and DNMT3a-mediated cytosine methylation in synthetic duplex DNA. We found that the replacement of 5mC at CpG site with a 5-hydroxymethylcytosine, 5-formylcytosine, 5-carboxylcytosine or...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4052722/ https://ncbi.nlm.nih.gov/pubmed/24789765 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4mb00150h |
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