A SNX3-dependent Retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

Wnt proteins are lipid modified glycoproteins that play a central role in development, adult tissue homeostasis and disease. Secretion of Wnt proteins is mediated by the Wnt-binding protein Wntless (Wls), which transports Wnt from the Golgi network to the cell surface for release. It has recently be...

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Autors principals: Harterink, Martin, Port, Fillip, Lorenowicz, Magdalena J., McGough, Ian J., Silhankova, Marie, Betist, Marco C., van Weering, Jan R. T., van Heesbeen, Roy G. H. P., Middelkoop, Teije C., Basler, Konrad, Cullen, Peter J., Korswagen, Hendrik C.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052212/
https://ncbi.nlm.nih.gov/pubmed/21725319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2281
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