SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless

Drosophila Wingless (Wg) acts as a morphogen during development. Wg secretion is controlled by a seven-pass transmembrane cargo Wntless (Wls). We have recently identified retromer as a key regulator involved in Wls trafficking. As sorting nexin (SNX) molecules are essential components of the retrome...

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Bibliografiske detaljer
Main Authors: Zhang, Peng, Wu, Yihui, Belenkaya, Tatyana Y, Lin, Xinhua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3357989/
https://ncbi.nlm.nih.gov/pubmed/22041890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.167
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