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SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless
Drosophila Wingless (Wg) acts as a morphogen during development. Wg secretion is controlled by a seven-pass transmembrane cargo Wntless (Wls). We have recently identified retromer as a key regulator involved in Wls trafficking. As sorting nexin (SNX) molecules are essential components of the retrome...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3357989/ https://ncbi.nlm.nih.gov/pubmed/22041890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2011.167 |
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