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C. elegans AP-2 and Retromer Control Wnt Secretion by Regulating MIG-14/Wntless

While endocytosis can regulate morphogen distribution, its precise role in shaping these gradients is unclear. Even more enigmatic is the role of retromer, a complex that shuttles proteins between endosomes and the Golgi apparatus, in Wnt gradient formation. Here we report that DPY-23, the C. elegan...

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Bibliografiske detaljer
Main Authors: Pan, Chun-Liang, Baum, Paul D., Gu, Mingyu, Jorgensen, Erik M., Clark, Scott G., Garriga, Gian
Format: Artigo
Sprog:Inglês
Udgivet: 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2709403/
https://ncbi.nlm.nih.gov/pubmed/18160346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.12.001
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