Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells

Wnt proteins are lipid-modified glycoproteins that have important roles in development, adult tissue homeostasis and disease. Secretion of Wnt proteins from producing cells is mediated by the Wnt-binding protein MIG-14/Wls, which binds Wnt in the Golgi network and transports it to the cell surface f...

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Main Authors: Silhankova, Marie, Port, Fillip, Harterink, Martin, Basler, Konrad, Korswagen, Hendrik C
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2010
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3018790/
https://ncbi.nlm.nih.gov/pubmed/21076391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.278
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