Finding Inhibitors of Mutant Superoxide Dismutase-1 for Amyotrophic Lateral Sclerosis Therapy from Traditional Chinese Medicine

Superoxide dismutase type 1 (SOD1) mutations cause protein aggregation and decrease protein stability, which are linked to amyotrophic lateral sclerosis (ALS) disease. This research utilizes the world's largest traditional Chinese medicine (TCM) database to search novel inhibitors of mutant SOD...

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Bibliografiska uppgifter
Huvudupphovsmän: Huang, Hung-Jin, Chang, Tung-Ti, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Materialtyp: Artigo
Språk:Inglês
Publicerad: Hindawi Publishing Corporation 2014
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052194/
https://ncbi.nlm.nih.gov/pubmed/24963318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/156276
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