Finding Inhibitors of Mutant Superoxide Dismutase-1 for Amyotrophic Lateral Sclerosis Therapy from Traditional Chinese Medicine

Superoxide dismutase type 1 (SOD1) mutations cause protein aggregation and decrease protein stability, which are linked to amyotrophic lateral sclerosis (ALS) disease. This research utilizes the world's largest traditional Chinese medicine (TCM) database to search novel inhibitors of mutant SOD...

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Autori principali: Huang, Hung-Jin, Chang, Tung-Ti, Chen, Hsin-Yi, Chen, Calvin Yu-Chian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052194/
https://ncbi.nlm.nih.gov/pubmed/24963318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/156276
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