Conditional Ablation of Astroglial CCL2 Suppresses CNS Accumulation of M1 Macrophages and Preserves Axons in Mice with MOG Peptide EAE

Current multiple sclerosis (MS) therapies only partially prevent chronically worsening neurological deficits, which are largely attributable to progressive loss of CNS axons. Prior studies of experimental autoimmune encephalomyelitis (EAE) induced in C57BL/6 mice by immunization with myelin oligoden...

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Bibliographische Detailangaben
Hauptverfasser: Moreno, Monica, Bannerman, Peter, Ma, Joyce, Guo, Fuzheng, Miers, Laird, Soulika, Athena M., Pleasure, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2014
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051973/
https://ncbi.nlm.nih.gov/pubmed/24920622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1137-14.2014
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