Conditional Ablation of Astroglial CCL2 Suppresses CNS Accumulation of M1 Macrophages and Preserves Axons in Mice with MOG Peptide EAE

Current multiple sclerosis (MS) therapies only partially prevent chronically worsening neurological deficits, which are largely attributable to progressive loss of CNS axons. Prior studies of experimental autoimmune encephalomyelitis (EAE) induced in C57BL/6 mice by immunization with myelin oligoden...

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Detalhes bibliográficos
Main Authors: Moreno, Monica, Bannerman, Peter, Ma, Joyce, Guo, Fuzheng, Miers, Laird, Soulika, Athena M., Pleasure, David
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051973/
https://ncbi.nlm.nih.gov/pubmed/24920622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1137-14.2014
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