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Cas9 as a versatile tool for engineering biology

RNA-guided Cas9 nucleases derived from clustered regularly interspaced short palindromic repeats (CRISPR)-Cas systems have dramatically transformed our ability to edit the genomes of diverse organisms. We believe tools and techniques based on Cas9, a single unifying factor capable of colocalizing RN...

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Detalhes bibliográficos
Main Authors: Mali, Prashant, Esvelt, Kevin M, Church, George M
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051438/
https://ncbi.nlm.nih.gov/pubmed/24076990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.2649
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