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Unraveling the Differences of the Hydrolytic Activity of Trypanosoma cruzitrans-Sialidase and Trypanosoma rangeli Sialidase: A Quantum Mechanics–Molecular Mechanics Modeling Study

[Image: see text] Chagas’ disease, also known as American trypanosomiasis, is a lethal, chronic disease that currently affects more than 10 million people in Central and South America. The trans-sialidase from Trypanosoma cruzi (T. cruzi, TcTS) is a crucial enzyme for the survival of this parasite:...

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Detaylı Bibliyografya
Asıl Yazarlar: Bueren-Calabuig, Juan A., Pierdominici-Sottile, Gustavo, Roitberg, Adrian E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2014
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4051249/
https://ncbi.nlm.nih.gov/pubmed/24814976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp412294r
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