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The many faces of HMGB1: molecular structure-functional activity in inflammation, apoptosis, and chemotaxis
HMGB1 is a ubiquitous nuclear protein present in almost all cell types. In addition to its intracellular functions, HMGB1 can be extracellularly released, where it mediates activation of innate immune responses, including chemotaxis and cytokine release. HMGB1 contains three conserved redox-sensitiv...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Leukocyte Biology
2013
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4051189/ https://ncbi.nlm.nih.gov/pubmed/23446148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1212662 |
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