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PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy
PURPOSE: Activating extrinsic apoptotic pathways targeting death receptors (DR) using agonistic antibodies or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is promising for cancer therapy. However, most pancreatic cancers are resistant to TRAIL therapy. The present studies aimed to...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050702/ https://ncbi.nlm.nih.gov/pubmed/23833311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0516 |
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