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PARP-1 regulates resistance of pancreatic cancer to TRAIL therapy

PURPOSE: Activating extrinsic apoptotic pathways targeting death receptors (DR) using agonistic antibodies or tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is promising for cancer therapy. However, most pancreatic cancers are resistant to TRAIL therapy. The present studies aimed to...

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Detaylı Bibliyografya
Asıl Yazarlar: Yuan, Kaiyu, Sun, Yong, Zhou, Tong, McDonald, Jay, Chen, Yabing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050702/
https://ncbi.nlm.nih.gov/pubmed/23833311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-0516
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