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The long non-coding RNA HOTAIR enhances pancreatic cancer resistance to TNF-related apoptosis-inducing ligand

Pancreatic cancer is a malignant neoplasm with a high mortality rate. Therapeutic agents that activate TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis have shown promising efficacy, but many pancreatic cancers are resistant to TRAIL therapy. Epigenetic regulation plays important role...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yang, Shan-zhong, Xu, Fei, Zhou, Tong, Zhao, Xinyang, McDonald, Jay M., Chen, Yabing
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481552/
https://ncbi.nlm.nih.gov/pubmed/28476883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.786830
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