Regulation of the Src-PP2A Interaction in Tumor Necrosis Factor (TNF)-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis

TNF-related apoptosis-inducing ligand (TRAIL) selectively induces apoptosis in transformed and tumor cells but not in normal cells, making it a promising agent for cancer therapy. However, many cancer cells are resistant to TRAIL, and the underlying mechanisms are not fully understood. Here, we show...

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Detalhes bibliográficos
Main Authors: Xu, Jing, Xu, Zhengfan, Zhou, Jun-Ying, Zhuang, Zhengping, Wang, Enhua, Boerner, Julie, Wu, Gen Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829172/
https://ncbi.nlm.nih.gov/pubmed/24100030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.508093
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