PILRα and PILRβ have a siglec fold and provide the basis of binding to sialic acid

Paired immunoglobulin-like type 2 receptor α (PILRα) and β (PILRβ) belong to the PILR family and are related to innate immune regulation in various species. Despite their high sequence identity, PILRα and PILRβ are shown to have variant sialic acid (SA) binding avidities. To explore the molecular ba...

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Detalhes bibliográficos
Main Authors: Lu, Qiong, Lu, Guangwen, Qi, Jianxun, Wang, Han, Xuan, Yifang, Wang, Qihui, Li, Yan, Zhang, Yanfang, Zheng, Chunfu, Fan, Zheng, Yan, Jinghua, Gao, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050567/
https://ncbi.nlm.nih.gov/pubmed/24843130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320716111
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