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Structural basis of collagen recognition by human osteoclast-associated receptor and design of osteoclastogenesis inhibitors

Human osteoclast-associated receptor (OSCAR) is an immunoglobulin (Ig)-like collagen receptor that is up-regulated on osteoclasts during osteoclastogenesis and is expressed in a range of myeloid cells. As a member of the leukocyte receptor complex family of proteins, OSCAR shares a high degree of se...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Haywood, Joel, Qi, Jianxun, Chen, Chun-Chi, Lu, Guangwen, Liu, Yingxia, Yan, Jinghua, Shi, Yi, Gao, George F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4743793/
https://ncbi.nlm.nih.gov/pubmed/26744311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522572113
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