Siglecs Facilitate HIV-1 Infection of Macrophages through Adhesion with Viral Sialic Acids

BACKGROUND: Human immunodeficiency virus type 1 (HIV-1) infects macrophages effectively, despite relatively low levels of cell surface-expressed CD4. Although HIV-1 infections are defined by viral tropisms according to chemokine receptor usage (R5 and X4), variations in infection are common within b...

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Detalhes bibliográficos
Main Authors: Zou, Zhongcheng, Chastain, Ashley, Moir, Susan, Ford, Jennifer, Trandem, Kathryn, Martinelli, Elena, Cicala, Claudia, Crocker, Paul, Arthos, James, Sun, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3169630/
https://ncbi.nlm.nih.gov/pubmed/21931755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024559
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