Synthetic di-sulfated iduronic acid attenuates asthmatic response by blocking T-cell recruitment to inflammatory sites

Identification of carbohydrate sequences that determine affinity to specific chemokines is a critical step for strategies to interfere with chemokine-mediated leukocyte trafficking. Here, we first characterized the development of allergic asthma in Tie2-dependent and inducible Ext1-knockout (Tie2-Ex...

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Detalhes bibliográficos
Main Authors: Nonaka, Motohiro, Bao, Xingfeng, Matsumura, Fumiko, Götze, Sebastian, Kandasamy, Jeyakumar, Kononov, Andrew, Broide, David H., Nakayama, Jun, Seeberger, Peter H., Fukuda, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050563/
https://ncbi.nlm.nih.gov/pubmed/24835176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1319870111
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