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Short synthetic sequence for 2-sulfation of α-L-iduronate glycosides
Hunter syndrome (mucopolysaccharidosis-II) is caused by deficiency of the lysosomal enzyme iduronate-2-sulfatase. The assay of this sulfatase requires the use of α-L-iduronate glycosides containing a sulfate at the 2-position. We report a simple, three-step procedure for introduction of sulfate at t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680446/ https://ncbi.nlm.nih.gov/pubmed/19356745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.carres.2009.03.012 |
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