Endothelial Heparan Sulfate Controls Chemokine Presentation in Recruitment of Lymphocytes and Dendritic Cells to Lymph Nodes

Heparan sulfate can bind several adhesion molecules involved in lymphocyte trafficking. However, the in vivo function of endothelial heparan sulfate in lymphocyte homing and stimulation of the immune response has not been elucidated. Here, we generated mutant mice deficient in the enzyme Ext1, which...

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Hlavní autoři: Bao, Xingfeng, Moseman, E. Ashley, Saito, Hideo, Petryanik, Bronislawa, Thiriot, Aude, Hatakeyama, Shingo, Ito, Yuki, Kawashima, Hiroto, Yamaguchi, Yu, Lowe, John B, von Andrian, Ulrich H, Fukuda, Minoru
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996097/
https://ncbi.nlm.nih.gov/pubmed/21093315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.10.018
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