Endothelial Heparan Sulfate Controls Chemokine Presentation in Recruitment of Lymphocytes and Dendritic Cells to Lymph Nodes

Heparan sulfate can bind several adhesion molecules involved in lymphocyte trafficking. However, the in vivo function of endothelial heparan sulfate in lymphocyte homing and stimulation of the immune response has not been elucidated. Here, we generated mutant mice deficient in the enzyme Ext1, which...

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Detalhes bibliográficos
Main Authors: Bao, Xingfeng, Moseman, E. Ashley, Saito, Hideo, Petryanik, Bronislawa, Thiriot, Aude, Hatakeyama, Shingo, Ito, Yuki, Kawashima, Hiroto, Yamaguchi, Yu, Lowe, John B, von Andrian, Ulrich H, Fukuda, Minoru
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996097/
https://ncbi.nlm.nih.gov/pubmed/21093315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.10.018
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