Glutamate carboxypeptidase II is not an amyloid peptide-degrading enzyme

Glutamate carboxypeptidase II (GCPII) is an exopeptidase that catalyzes the hydrolysis of N-acetylated aspartate-glutamate (NAAG) to N-acetyl aspartate (NAA) and glutamate. Consequently, GCPII inhibition has been of interest for the treatment of central and peripheral nervous system diseases associa...

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Autori principali: Alt, Jesse, Stathis, Marigo, Rojas, Camilo, Slusher, Barbara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2013
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050421/
https://ncbi.nlm.nih.gov/pubmed/23525278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-225102
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