An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case-control studies

BACKGROUND: Knee osteoarthritis (OA) is a complex disease involving both biomechanical and metabolic factors that alter the tissue homeostasis of articular cartilage and subchondral bone. The catabolic activities of extracellular matrix degradation products, especially fibronectin (FN), have been im...

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Hlavní autoři: Yang, Hsin-Yi, Su, Sui-Lung, Peng, Yi-Jen, Wang, Chih-Chien, Lee, Herng-Sheng, Salter, Donald M, Lee, Chian-Her
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050217/
https://ncbi.nlm.nih.gov/pubmed/24886251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-173
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