An intron polymorphism of the fibronectin gene is associated with end-stage knee osteoarthritis in a Han Chinese population: two independent case-control studies

BACKGROUND: Knee osteoarthritis (OA) is a complex disease involving both biomechanical and metabolic factors that alter the tissue homeostasis of articular cartilage and subchondral bone. The catabolic activities of extracellular matrix degradation products, especially fibronectin (FN), have been im...

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Detalhes bibliográficos
Main Authors: Yang, Hsin-Yi, Su, Sui-Lung, Peng, Yi-Jen, Wang, Chih-Chien, Lee, Herng-Sheng, Salter, Donald M, Lee, Chian-Her
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050217/
https://ncbi.nlm.nih.gov/pubmed/24886251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-173
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