Dexamethasone Down-regulates Osteocalcin in Bone Cells through Leptin Pathway

Glucocorticoid therapy, especially at higher doses, is associated with significant adverse side effects including osteoporosis. Leptin, secreted from adipose tissue, has diverse effects on bone tissue regulation. As glucocorticoids stimulate leptin synthesis and secretion directly in adipose tissue...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Med Sci
Main Authors: Chen, Shu-Mei, Peng, Yi-Jen, Wang, Chih-Chien, Su, Sui-Lung, Salter, Donald M, Lee, Herng-Sheng
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2018
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859774/
https://ncbi.nlm.nih.gov/pubmed/29559840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijms.21881
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