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Reversing deleterious protein aggregation with re-engineered protein disaggregases

Aberrant protein folding is severely problematic and manifests in numerous disorders, including amyotrophic lateral sclerosis (ALS), Parkinson disease (PD), Huntington disease (HD), and Alzheimer disease (AD). Patients with each of these disorders are characterized by the accumulation of mislocalize...

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Sonraí Bibleagrafaíochta
Main Authors: Jackrel, Meredith E, Shorter, James
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050135/
https://ncbi.nlm.nih.gov/pubmed/24694655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28709
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