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Reversing deleterious protein aggregation with re-engineered protein disaggregases

Aberrant protein folding is severely problematic and manifests in numerous disorders, including amyotrophic lateral sclerosis (ALS), Parkinson disease (PD), Huntington disease (HD), and Alzheimer disease (AD). Patients with each of these disorders are characterized by the accumulation of mislocalize...

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Hlavní autoři: Jackrel, Meredith E, Shorter, James
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050135/
https://ncbi.nlm.nih.gov/pubmed/24694655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28709
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