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Reversing deleterious protein aggregation with re-engineered protein disaggregases
Aberrant protein folding is severely problematic and manifests in numerous disorders, including amyotrophic lateral sclerosis (ALS), Parkinson disease (PD), Huntington disease (HD), and Alzheimer disease (AD). Patients with each of these disorders are characterized by the accumulation of mislocalize...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4050135/ https://ncbi.nlm.nih.gov/pubmed/24694655 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.28709 |
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