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Deubiquitinating enzyme regulation of the p53 pathway: A lesson from Otub1

Deubiquitination has emerged as an important mechanism of p53 regulation. A number of deubiquitinating enzymes (DUBs) from the ubiquitin-specific protease family have been shown to regulate the p53-MDM2-MDMX networks. We recently reported that Otub1, a DUB from the OTU-domain containing protease fam...

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Hlavní autoři: Sun, Xiao-Xin, Dai, Mu-Shui
Médium: Artigo
Jazyk:Inglês
Vydáno: Baishideng Publishing Group Inc 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4050119/
https://ncbi.nlm.nih.gov/pubmed/24920999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4331/wjbc.v5.i2.75
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