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Clostridium difficile binary toxin CDT: Mechanism, epidemiology, and potential clinical importance

Binary toxin (CDT) is frequently observed in Clostridium difficile strains associated with increased severity of C. difficile infection (CDI). CDT belongs to the family of binary ADP-ribosylating toxins consisting of two separate toxin components: CDTa, the enzymatic ADP-ribosyltransferase which mod...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gerding, Dale N, Johnson, Stuart, Rupnik, Maja, Aktories, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049931/
https://ncbi.nlm.nih.gov/pubmed/24253566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.26854
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