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Early detection of thrombin activity in neuroinflammatory disease

Although multiple sclerosis (MS) has been associated with the coagulation system, the temporal and spatial regulation of coagulation activity in neuroinflammatory lesions is unknown. Using a novel molecular probe, we characterized the activity pattern of thrombin, the central protease of the coagula...

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Detalhes bibliográficos
Main Authors: Davalos, Dimitrios, Baeten, Kim M, Whitney, Michael A, Mullins, Eric S, Friedman, Beth, Olson, Emilia S, Ryu, Jae Kyu, Smirnoff, Dimitri S, Petersen, Mark A, Bedard, Catherine, Degen, Jay L, Tsien, Roger Y, Akassoglou, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049631/
https://ncbi.nlm.nih.gov/pubmed/24740641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24078
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