تحميل...
Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation
Blood-brain barrier disruption, microglial activation and neurodegeneration are hallmarks of multiple sclerosis. However, the initial triggers that activate innate immune responses and their role in axonal damage remain unknown. Here we show that the blood protein fibrinogen induces rapid microglial...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Nature Pub. Group
2012
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3514498/ https://ncbi.nlm.nih.gov/pubmed/23187627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2230 |
| الوسوم: |
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