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In vivo two-photon microscopy protocol for imaging microglial responses and spine elimination at sites of fibrinogen deposition in mouse brain

Deposition of the blood coagulation factor fibrinogen in the central nervous system is a hallmark of neurological diseases with blood-brain barrier disruption. We describe in vivo two-photon imaging of microglial responses and neuronal spine elimination to either intracortical microinjection of fibr...

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Bibliografiske detaljer
Udgivet i:STAR Protoc
Main Authors: Tognatta, Reshmi, Merlini, Mario, Yan, Zhaoqi, Schuck, Renaud, Davalos, Dimitrios, Akassoglou, Katerina
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8259313/
https://ncbi.nlm.nih.gov/pubmed/34258598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xpro.2021.100638
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