Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease

We hypothesize that the phenomenon of allele-specific methylation (ASM) may underlie the phenotypic effects of multiple variants identified by Genome-Wide Association studies (GWAS). We evaluate ASM in a human population and document its genome-wide patterns in an initial screen at up to 380,678 sit...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Hutchinson, John N., Raj, Towfique, Fagerness, Jes, Stahl, Eli, Viloria, Fernando T., Gimelbrant, Alexander, Seddon, Johanna, Daly, Mark, Chess, Andrew, Plenge, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4049588/
https://ncbi.nlm.nih.gov/pubmed/24911414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098464
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge