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Crosstalk of Genetic Variants, Allele-Specific DNA Methylation, and Environmental Factors for Complex Disease Risk

Over the past decades, genome-wide association studies (GWAS) have identified thousands of phenotype-associated DNA sequence variants for potential explanations of inter-individual phenotypic differences and disease susceptibility. However, it remains a challenge for translating the associations int...

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Bibliographic Details
Published in:Front Genet
Main Authors: Wang, Huishan, Lou, Dan, Wang, Zhibin
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6334214/
https://ncbi.nlm.nih.gov/pubmed/30687383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2018.00695
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