(Epi)Genetic Analyses of Age-Related Macular Degeneration: Case-control and Discordant Twin Studies

BACKGROUND/AIMS: Phenotypic discordance in monozygotic (MZ) twin pairs can have an epigenetic or genetic basis. Although age-related macular degeneration (AMD) has a strong genetic component, few studies have addressed it’s epigenetic basis. METHODS: Using SNP arrays, we evaluated differences in cop...

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Pubblicato in:Hum Hered
Autori principali: Hutchinson, John N., Fagerness, Jes, Kirby, Andrew, Reynolds, Robyn, Zak, Alex, Gimelbrant, Alexander, Plenge, Robert, Daly, Mark, Chess, Andrew, Seddon, Johanna M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476332/
https://ncbi.nlm.nih.gov/pubmed/25033836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000362814
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