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Thermodynamics of the DNA Damage Repair Steps of Human 8-Oxoguanine DNA Glycosylase
Human 8-oxoguanine DNA glycosylase (hOGG1) is a key enzyme responsible for initiating the base excision repair of 7,8-dihydro-8-oxoguanosine (oxoG). In this study a thermodynamic analysis of the interaction of hOGG1 with specific and non-specific DNA-substrates is performed based on stopped-flow kin...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4049573/ https://ncbi.nlm.nih.gov/pubmed/24911585 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098495 |
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