In vivo Drug Interactions of the Teratogen Thalidomide with Midazolam: Heterotropic Cooperativity of Human Cytochrome P450 in Humanized TK-NOG Mice

Lignende værker

• Simulation of Human Plasma Concentrations of Thalidomide and Primary 5-Hydroxylated Metabolites Explored with Pharmacokinetic Data in Humanized TK-NOG mice
  af: Nishiyama, Sayako, et al.
  Udgivet: (2015)
• Drug Interactions of Thalidomide with Midazolam and Cyclosporine A: Heterotropic Cooperativity of Human Cytochrome P450 3A5
  af: Okada, Yusuke, et al.
  Udgivet: (2009)
• In vivo Formation of Dihydroxylated and Glutathione Conjugate Metabolites derived from Thalidomide and 5-Hydroxythalidomide in Humanized TK-NOG mice
  af: Yamazaki, Hiroshi, et al.
  Udgivet: (2012)
• In Vivo Formation of a Glutathione Conjugate Derived from Thalidomide in Humanized uPA-NOG Mice
  af: Yamazaki, Hiroshi, et al.
  Udgivet: (2011)
• Thalidomide Increases Human Hepatic Cytochrome P450 3A Enzymes by Direct Activation of Pregnane X Receptor
  af: Murayama, Norie, et al.
  Udgivet: (2014)