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Discovery and saturation analysis of cancer genes across 21 tumor types
While a few cancer genes are mutated in a high proportion of tumors of a given type (>20%), most are mutated at intermediate frequencies (2–20%). To explore the feasibility of creating a comprehensive catalog of cancer genes, we analyzed somatic point mutations in exome sequence from 4,742 tumor-...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4048962/ https://ncbi.nlm.nih.gov/pubmed/24390350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12912 |
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