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Continuous separation of protein loaded nanoparticles by simulated moving bed chromatography

For scale up and efficient production of protein loaded nanoparticles continuous separation by size exclusion chromatography in simulated moving bed (SMB) mode helps do reduce unbound protein concentration and increase yields for perfectly covered particles. Silica nanoparticles were loaded with an...

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Bibliografiske detaljer
Main Authors: Satzer, Peter, Wellhoefer, Martin, Jungbauer, Alois
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4048465/
https://ncbi.nlm.nih.gov/pubmed/24866563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2014.04.093
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